Modern Therapy for Depression, Mood Disorders, and Chronic Pain
"You can't change the beginning, but you can start where you are andChange the Ending."
- C.S. Lewis
For more than 50 years, ketamine has been safely administered to induce anesthesia on the battlefield, in emergency rooms, and in surgical settings. In recent years, ketamine has been used off-label to successfully treat depression, mood disorders, and chronic pain.
"About 80% of people who were prescribed ketamine showed relief from depressive symptoms. The benefits discovered placed ketamine in the World Health Organization's list of essential medicines, which encourages its use far and wide."
Ketamine for Depression & Anxiety
The former director of the National Institute of Mental Health, reported: “Recent data suggest that ketamine, given intravenously, might be the most important breakthrough in antidepressant treatment in decades.”
Similarly, “several studies now provide evidence of ketamine hydrochloride’s ability to produce rapid and robust antidepressant effects in patients with mood and anxiety disorders that were previously resistant to treatment,” said three psychiatrists in the American Medical Association's Consensus Statement on the Use of Ketamine in the Treatment of Mood Disorders.
Ketamine for Chronic Pain
Are you suffering from chronic neuropathic pain, complex regional pain syndrome, post-herpetic neuralgia, migraine headaches, or chronic post-surgical pain? Affordable Ketamine Clinic has provided relief for numerous patients suffering from various types of chronic pain. If you have found opioids to be ineffective, desire to decrease dependence on opioids, or are seeking alternative treatment, you are encouraged to try IV infusion pain treatment. We currently treat pain with a formula of ketamine, lidocaine, and magnesium sulfate. The analgesic effects of this regimen can last up to 12 weeks.
Ketamine for Post-Traumatic Stress Disorder
Researchers studying the biological foundations of PTSD have found “mounting evidence for a role of the excitatory neurotransmitter glutamate in stress responsiveness, the formation of traumatic memories, and the pathophysiology of PTSD. Ketamine treatment targets these biological elements. In a double-blind study, scientists found that ketamine infusion therapy "rapidly and significantly reduces symptom severity in patients with PTSD compared with midazolam."
Ketamine for Depression & Anxiety
"One likely target for ketamine is NMDA receptors in the brain. By binding to these receptors, ketamine appears to increase the amount of a neurotransmitter called glutamate in the spaces between neurons. Glutamate then activates connections in another receptor, called the AMPA receptor..."
Ketamine for Chronic Pain
Are you suffering from chronic neuropathic pain, complex regional pain syndrome, post-herpetic neuralgia, migraine headaches, or chronic post-surgical pain? Affordable Ketamine Clinic has provided relief for numerous patients suffering from various types of chronic pain.
Ketamine for PTSD
"Ketamine-mediated synaptic plasticity changes appear to occur within a matter of hours after ketamine administration. “The current thinking is that eventually, 6 to 12 weeks after initiating treatment with traditional antidepressants, dendritic growth and increased synaptic connections occur but with ketamine, these can occur within 24 hours of the infusion,” Dr Masand said..."
Ketamine for Obsessive Compulsive Disorder
A recent study of the effect of ketamine on OCD patients showed that they "reported dramatic decreases in their obsessive-compulsive symptoms midway through a 40-minute infusion," and that at least half of those patients reported that their obsessive-compulsive symptoms were diminished the following week. We recommend six 40-minute treatments over two weeks for a maximum effect. One patient in the study reported that, after ketamine therapy, “I tried to have OCD thoughts, but I couldn’t.”
Ketamine for Bipolar Disorder
Individuals suffering from bipolar disorder frequently try to find relief from their symptoms in the depressive phases of the illness. In a recent study published in the Archives of General Psychiatry, scientists demonstrated that "40 minutes after receiving ketamine, [patients'] depressive symptoms lessened significantly." This dramatic change resulted from a single intravenous infusion of ketamine, which is an NMDA (glutamate) receptor antagonist. We recommend six 40-minute treatments over two weeks to ensure that improvement lasts for the maximum possible time before you need a booster dose.
Ketamine for Suicide Ideation
Research on the use of ketamine to reduce or eliminate suicide ideation is promising. An intensive study of 18 patients with acute suicidal ideation who required hospitalization randomly assigned the patients to receive either intravenous ketamine or a saline placebo. The study had excellent results, with 88% of the ketamine group achieving remission of suicidal thoughts compared with 33% of the placebo group.
Does insurance cover ketamine infusions?
What's the age range for ketamine patients?
Can I continue taking my regular prescription?
Generally, you should continue taking the medications prescribed by your medical provider and consult with them about the addition of ketamine to your regimen. It is important to know that Lamictal (Lamotrigine) blocks the therapeutic effects of ketamine. Obtain advice and authorization from your prescriber to cease taking Lamictal for at least 2 weeks before initiating ketamine treatment. Narcotics and benzodiazepines may blunt the effectiveness of ketamine. (Benzodiazepines include Valium, Versed, Ativan, Xanax, Klonopin, and Lorazepam.)
Will I need to be on ketamine forever?
Why is ketamine called a "miracle drug"?
Yale Medicine reports ketamine being one of the biggest breakthroughs in depression research. Ketamine is referred to a miracle drug because of how quickly it works.
What are common side effects to ketamine treatments?
Most patients will experience feelings of dissociation and a little dizziness. Some may feel nausea, sleepiness, headaches, or weakness. These symptoms usually are mild and generally are resolved within a few hours of the infusion.
How long should I refrain from alcohol before a ketamine infusion?
What does a ketamine infusion feel like?
When treatment begins, patients enter a dream-like state and may have some time perception distortion and disassociation, but they don’t fall asleep. Many patients will report feeling relaxed within a few minutes. We have a special “relax” treatment room, where patients will settle into a soft leather recliner and begin their infusion therapy.
How often will I need a ketamine infusion?
Does the clinic offer evening appointments?
We answer our phones from 9:00 a.m. to 9:00 p.m. We generally schedule infusion appointments between 2:00 p.m. and 8:00 p.m., but will work with you to accommodate your work schedule.
What are the advantages of ketamine infusion therapy versus intramuscular injections or esketamine nasal spray?
Is ketamine FDA-approved?
Ketamine is a drug approved by the United States Food and Drug Administration (FDA) for use in anesthesia. It has been used off-label for depression, mood disorder, and pain treatment successfully for more than a decade. Off-label prescribing means that you are given a drug that the FDA has approved to treat a condition different from your condition. This practice is legal and common--one in five prescriptions written today are for off-label use.
Is the treatment for pain different from the treatment for mood disorders?
Infusion therapy for treatment of chronic pain employs a larger dose of ketamine and includes NMDA blockers, creating a synergistic effect. Pain treatments are usually an hour and a half, while mood disorder treatments are one hour.
How does infusion therapy for pain work?
If you have found opioids to be ineffective, desire to decrease dependence on opioids, or are seeking alternative treatment, you are encouraged to try IV infusion pain treatment. Studies show that certain pain syndromes that are modulated by N-methyl-D-aspartate (NMDA) receptors may respond to a regimen of NMDA blockers—we currently treat pain with a formula of ketamine, lidocaine, and magnesium sulfate. The analgesic effects of this regimen can last up to 12 weeks. The liver metabolite norketamine may partially account for the desired long-term effects, as well as the desensitization of hyperalgesia associated with chronic pain.
Is ketamine treatment appropriate for all types of chronic pain?
Not everyone is a candidate for chronic pain therapy, including patients with poorly controlled cardiovascular disease, severe liver disease, substance abuse problems, elevated intracranial pressure, and glaucoma. Please see your treating doctor or nurse practitioner to obtain a referral for chronic pain treatment.